Thursday 28 March 2024

Antibiotic Resistance Market To Reach $12.48 Billion By 2030

 


The global Antibiotic Resistance Market size is expected to reach USD 12.48 billion by 2030, registering a CAGR of 5.27% from 2024 to 2030, according to a new report by Grand View Research, Inc. Rise in the number of antibiotic-resistant infections due to misuse or overuse of antibiotics is a major factor attributing to market growth. Moreover, the increasing patient base across the globe and high costs associated with the treatment of diseases is anticipated to boost the market growth over the forecast period.

The prevalence of gram-negative infections is increasing at an alarming rate. These infections have lesser treatment options available in the market. The high unmet needs result in high demand for new therapies and, therefore, small and medium-sized pharmaceutical companies are actively involved in the development of novel treatment options. Moreover, the government and other organizations are also aiding research activities to drive the development of innovative therapies.

Multiple mid-level biotechnology companies have entered the arena with targeted therapies for antibiotic-resistant infections. Various manufacturers are developing therapies, especially for drug-resistant infections, that target a smaller population subset.

The U.S. government in alliance with BARDA is supporting several companies to boost the development of new therapies for antibiotic-resistant diseases. BARDA has also been associated with pharmaceutical companies such as GSK; Tetraphase; Basilea; Astra Zeneca; and many more. Many countries and international organizations have formed dedicated groups or alliances to monitor and study the pattern of drug-resistant infections.

For instance, the WHO has introduced the Global Antimicrobial Resistance Surveillance System (GLASS) to monitor antibiotic-resistant infections at a global level. Similarly, the Public Health Agency of Canada has introduced the Canadian Antimicrobial Resistance Surveillance System (CARSS) to study drug-resistant infections pattern at the country level.

However, according to a review published by WHO in March 2023, the antibiotics pipeline activities are limited, with only 12 new antibiotics being approved between 2017 and 2021. The review further stated that there are only 27 new candidates under development, out of which only 6 are considered “innovative” enough to be capable of overcoming antibiotic resistance as defined by WHO.

Related Press Release@ Antibiotic Resistance Market Report

Antibiotic Resistance Market Report Highlights

  • In 2023, cUTI accounted for the largest market share and is anticipated to maintain its dominance in the global market in the coming years
  • Combination drugs are expected to grow at the fastest CAGR over the forecast period
  • North America dominated the antibiotic resistance industry in 2023. The target goals set by the U.S. national action plan in response to the significant burden of resistant gram-positive and negative infections is the key factor driving the market
  • Asia Pacific is set to witness the fastest growth over the forecast period due to excessive consumption of antibiotics, advancements in technology, and growing awareness about antibiotic resistance testing, treatment, & management of the same.

Antibiotic Resistance Market Report Scope

Report Attribute

Details

Market size value in 2024

USD 9.17 billion

Revenue forecast in 2030

USD 12.48 billion

Growth rate

CAGR of 5.27% from 2024 to 2030

Base year for estimation

2023

Historical data

2018 - 2022

Forecast period

2024 - 2030

 

Request For A Free Consultation @ https://www.grandviewresearch.com/request-free-consultation/5467/rfc

Antibiotic Resistance Market Segmentation

Grand View Research has segmented the global antibiotic resistance market based on disease, pathogen, drug class, mechanism of action, distribution channel, and region:

Antibiotic Resistance Disease Outlook (Revenue, USD Million, 2018 - 2030)

  • cUTI (Complicated Urinary Tract Infections)
  • CDI (Clostridioides difficile Infection)
  • ABSSSI (Acute bacterial skin and skin structure infections)
  • HABP (Hospital-acquired bacterial pneumonia)
  • CABP (Community-acquired pneumonia)
  • cIAI (Complicated intra-abdominal infection)
  • BSI (Bloodstream infection)

Antibiotic Resistance Pathogen Outlook (Revenue, USD Million, 2018 - 2030)

  • E. coli
  • K. pneumoniae
  • P. aeruginosa
  • S. aureus
  • A. baumannii
  • S. pneumoniae
  • H. influenzae
  • C. difficile
  • E. faecium

Antibiotic Resistance Drug Class Outlook (Revenue, USD Million, 2018 - 2030)

  • Oxazolidinones
  • Lipoglycopeptides
  • Tetracyclines
  • Combination therapies
  • Cephalosporins
  • Others

Antibiotic Resistance Mechanism of Action Outlook (Revenue, USD Million, 2018 - 2030)

  • Protein Synthesis Inhibitors
  • Cell Wall Synthesis Inhibitors
  • RNA Synthesis Inhibitors
  • DNA Synthesis Inhibitors
  • Others

Antibiotic Resistance Distribution Channel Outlook (Revenue, USD Million, 2018 - 2030)

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Antibiotic Resistance Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America
    • U.S.
    • Canada
  • Europe
    • UK
    • Germany
    • France
    • Italy
    • Spain
    • Denmark
    • Sweden
    • Norway
  • Asia Pacific
    • China
    • Japan
    • India
    • Australia
    • Thailand
    • South Korea
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Kuwait

About Us:
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, the company offers market intelligence studies ensuring relevant and fact-based research across a range of industries including technology, chemicals, materials, healthcare and energy.

Contact:
Sherry James

Corporate Sales Specialist, USA
Grand View Research, Inc
Phone: 1-415- 349-0058
Toll Free: 1-888- 202-9519
Email:
sales@grandviewresearch.com
For More Information:
https://www.grandviewresearch.com

Wednesday 27 March 2024

Liver Metastases Treatment Market Size is Predicted to Witness 7.3% CAGR till 2030



The global Liver Metastases Treatment Market is expected to reach USD 2.66 billion by 2030, according to a new report by Grand View Research, Inc., expanding at a CAGR of 7.3% from 2024 to 2030. Rising prevalence of target disease, advanced stage diagnosis for cancer in developing countries, and increasing number of products approvals is expected to drive the industry growth.

Colorectal cancer, breast cancer, and lung cancer are some of the key types that metastasize to the liver. The incidence of colorectal cancer is expected to increase from 1.88 million in 2020 to 2.45 million in 2030. Whereas the incidence of breast cancer is expected to increase from 2.26 million in 2020 to 2.74 million in 2030. The rising incidence of these primary indications is expected to drive space growth.

Majority of the cancer cases in low and middle-income countries are diagnosed at advanced stages where the availability of therapeutic options is low. The lack of availability of early diagnostics methods combined with uncertain reimbursement scenario for diagnostics are major reasons for delayed diagnosis. The advanced/metastatic stage of diagnosis provide lucrative growth opportunities in this space.

On the other hand, if cancers are diagnosed at advanced stages particularly in developing nations and LMICS, the treatment rate at such advanced stages is significantly less, due to unavailability of products and proper reimbursement. This factor is expected to restrain space growth.

List Of Key Players in the Liver Metastases Treatment Market

  • F. Hoffmann-La Roche Ltd.
  • AstraZeneca
  • Eli Lilly and Company
  • Bayer AG
  • Ono Pharmaceutical
  • Pfizer, Inc.
  • Bristol-Myers Squibb Company
  • Cadila Pharmaceuticals Ltd.

Related Press Release@ Liver Metastases Treatment Market Report

Liver Metastases Treatment Market Report Highlights

  • By treatment type, the targeted therapy segment dominated the market with a share of 56.52% to the presence of approved drugs with a price higher than traditional chemotherapy.
  • In 2023, colorectal cancer dominated the liver metastases treatment market with a share of 40.55%. Around 25-30% of all colorectal cancers metastasize to the liver. The availability of various treatment options for CCLM further contributed to the segments’ dominance.
  • Based on distribution channel, the market was dominated by the hospital pharmacies segment with a share of 60.07% in 2023. The high rate of hospitalization for the treatment of liver metastases is one of the major factors for the dominance of this segment.
  • By region, North America has a high revenue share in the global liver metastases treatment market in 2023. However, Asia Pacific is expected to be the fastest growing region during the forecast period.

Liver Metastases Treatment Market Report Scope 

Report Attribute

Details

Market size value in 2024

USD 1.74 billion

Revenue forecast in 2030

USD 2.66 billion

Growth rate

CAGR of 7.3% from 2024 to 2030

Base year for estimation

2023

Historical data

2018 - 2022

Forecast period

2024 - 2030

 

Request For A Free Consultation @ https://www.grandviewresearch.com/request-free-consultation/454161/rfc

Liver Metastases Treatment Market Segmentation

Grand View Research has segmented the global liver metastases treatment market report based on treatment type, primary cancer, distribution channel, and region:

Liver Metastases Treatment Type Outlook (Revenue, USD Million, 2018 - 2030)

  • Chemotherapy
  • Targeted Therapy
  • Immunotherapy

Liver Metastases Treatment Primary Cancer Outlook (Revenue, USD Million, 2018 - 2030)

  • Colorectal Cancer
  • Breast Cancer

Liver Metastases Treatment Distribution Channel Outlook (Revenue, USD Million, 2018 - 2030)

  • Hospital Pharmacies
  • Specialty Pharmacies

Liver Metastases Treatment Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America
    • U.S.
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Denmark
    • Sweden
    • Norway
  • Asia Pacific
    • China
    • India
    • Japan
    • Australia
    • South Korea
    • Thailand
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Kuwait
About Us:
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, the company offers market intelligence studies ensuring relevant and fact-based research across a range of industries including technology, chemicals, materials, healthcare and energy.

Contact:
Sherry James

Corporate Sales Specialist, USA
Grand View Research, Inc
Phone: 1-415- 349-0058
Toll Free: 1-888- 202-9519
Email:
sales@grandviewresearch.com
For More Information:
https://www.grandviewresearch.com

Advanced Therapy Medicinal Products CDMO Market To Reach $18.8 Billion By 2030

 


The global Advanced Therapy Medicinal Products CDMO Market size is expected to reach USD 18.8 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to register a CAGR of 18.92% from 2024 to 2030, owing to rising clinical trials for advanced therapy medicinal products and the increasing awareness among researchers about the benefits of advanced therapies, driving the advanced therapy medicinal products (ATMP) CDMO market growth. Tissue engineering has greatly benefited in recent years from technological development. The damaged tissues and organ function are replaced or restored using this technique. Similarly, gene and cell therapy are attracting a lot of patients for the treatment of rare diseases, whose incidence is rising globally.

With rising demand for robust disease treatment therapies, key players have focused their efforts to ramp up research and development for effective gene therapies that target the cause of disorder at a genomic level. According to ASGCT, the number of cell and gene therapies in the U.S. pipeline programs (phase I-III trials) increased from 483 in 2021 to 529 in 2022. Furthermore, the FDA delivers constant support for innovations in the gene therapy field via a number of policies with regard to product manufacturing. In January 2020, the agency released six final guidelines on the manufacturing and clinical development of safe & efficient gene therapy products.

Moreover, awareness about ATMP treatment options is being driven by initiatives aimed at informing the public about the benefits of these products, which, in turn, is leading to increased adoption of advanced therapies and fueling market growth for CDMOs. For instance, Alliance for Regenerative Medicine Foundation for Cell and Gene Medicine prioritizes activities for increasing public awareness through educational programs, underlining the clinical & societal benefits of regenerative medicine.

Increasing clinical trial activity along with new product launches generates growth opportunities for the market. As of 2022, there are 1451 ATMPs in preclinical stages and 535 are being studied in Phase 1 to 3 studies. Since August 2020, EMA has approved six of these additional ATMPs, and five more will be approved by 2023. In the UK, there were approximately 168 advanced therapy medicinal product trials underway in 2021, up from the 154 studies reported the year before, which is a 9% increase. 2021 saw a 32% increase in phase 1 trials, indicating a significant shift from experimental medicines to first-in-human studies.

On the other hand, key players are undertaking various strategic initiatives to introduce novel products, which is expected to propel market growth. For instance, in March 2021, CureVac N.V. signed a partnership agreement with Celonic Group, engaged in the manufacture of CVnCoV, CureVac’s mRNA-based COVID-19 vaccine candidate. CureVac's COVID-19 vaccine candidate is manufactured at Celonic's commercial manufacturing unit for ATMPs and biologics in Heidelberg, Germany. Under the terms of the commercial supply agreement, the Celonic facility could produce over 100 million doses of CVnCoV.

List of Key Players of Advanced Therapy Medicinal Products CDMO Market

  • Celonic
  • Bio Elpida
  • CGT Catapult
  • Rentschler Biopharma SE
  • AGC Biologics
  • Catalent
  • Lonza
  • WuXi Advanced Therapies
  • BlueReg
  • Minaris Regenerative Medicine
  • Patheon

Related Press Release@ Advanced Therapy Medicinal Products CDMO Market Report

Advanced Therapy Medicinal Products CDMO Market Report Highlights

  • The gene therapy segment held the largest share of over 49.2% in 2023. Increase in financial support and rise in number of clinical trials for gene therapies are driving demand for the gene therapy segment.
  • The cell therapy segment is expected to show lucrative growth over the forecast period. The field of cellular therapeutics is constantly advancing with inclusion of new cell types, which, in turn, provides ample opportunities for companies to enhance their market positions.
  • The oncology segment accounted for the largest revenue share in 2023. The segment’s dominance is attributed to disease burden, strategic initiatives undertaken by key players, and availability of advanced therapies used for treating various cancer indications.
  • The phase I segment dominated the market in 2023 due to growing R&D activities and increasing number of human trials for advanced therapies.
  • North America dominated the overall market share of 49.0% in 2023. This can be attributed to increasing outsourcing activities and rising awareness about advanced therapy.
  • The Asia Pacific region is expected to grow at the fastest CAGR over the forecast period due to the increasing demand for novel ATMPs and rising R&D activities to develop novel therapies.

Advanced Therapy Medicinal Products CDMO Market Report Scope

Report Attribute

Details

Market size value in 2024

USD 6.6 billion

Revenue forecast in 2030

USD 18.8 billion

Growth rate

CAGR of 18.92% from 2024 to 2030

Base year for estimation

2023

Historical data

2018 - 2022

Forecast period

2024 - 2030

 

Request For A Free Consultation @ https://www.grandviewresearch.com/request-free-consultation/452243/rfc

Advanced Therapy Medicinal Products CDMO Market Segmentation

Grand View Research has segmented the global advanced therapy medicinal products CDMO market report based on product, phase, indication, and region:

Advanced Therapy Medicinal Products CDMO Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Gene Therapy
  • Cell Therapy
  • Tissue Engineered
  • Others

Advanced Therapy Medicinal Products CDMO Phase Outlook (Revenue, USD Million, 2018 - 2030)

  • Phase I
  • Phase II
  • Phase III
  • Phase IV

Advanced Therapy Medicinal Products CDMO Indication Outlook (Revenue, USD Million, 2018 - 2030)

  • Oncology
  • Cardiology
  • Central nervous system
  • Musculoskeletal
  • Infectious disease
  • Dermatology
  • Endocrine, metabolic, genetic
  • Immunology & inflammation
  • Ophthalmology
  • Hematology
  • Gastroenterology
  • Others

Advanced Therapy Medicinal Products CDMO Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America
    • U.S.
    • Canada
  • Europe
    • UK
    • Germany
    • France
    • Italy
    • Spain
    • Denmark
    • Sweden
    • Norway
  • Asia Pacific
    • Japan
    • China
    • India
    • South Korea
    • Australia
    • Thailand
  • Latin America
    • Brazil
    • Mexico
    • Argentina
  • Middle East & Africa
    • South Africa
    • Saudi Arabia
    • UAE
    • Kuwait

Digital Pathology Market Size To Reach $1.73 Billion By 2030

The global  Digital Pathology Market  size is expected to reach USD 1.73 billion by 2030, registering a CAGR of 8.0% from 2024 to 2030, acco...