The global Downstream Processing Market size is expected to reach USD 94.8 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 15.0% from 2022 to 2030. The capacity requirements during the development of biologic drugs have changed over the past few years, wherein the demand for manufacturing high-volume products has shifted to developing small-volume, high-potency products. This creates new avenues for single-use technologies. A rise in the utilization of downstream processing techniques for the development of COVID-19 vaccines is a significant factor driving the market. The adoption of small-scale, single-use systems for process development and downstream processing is already high.
Thus, evolutionary changes are expected in the area of
single-use technologies for manufacturing small-volume, highly-potent drugs.
The development of novel film chemistries, closed systems, automation in
clinical-scale single-use systems, and smart sensors are some noteworthy
advancements in the field. A rise in applications of downstream processing for
the production of biopharmaceuticals is expected to bring growth opportunities
to the market. This has also led to an increase in strategic deals and
development in the market. For instance, in February 2021, Evozyne, LLC
collaborated with a leading rare disorders drug manufacturer for the production
and marketing of novel biopharmaceuticals for immune modulation.
Key players are investing in the bioprocessing of
vaccines and therapies for COVID-19 to increase their market share. For
instance, in May 2022, Lonza and ALSA Ventures are partnering to provide
biotech firms with development and manufacturing services. In May 2022, Lonza
added Titanium Dioxide-free white hard gelatin capsules to its Capsugel
Capsule Line. The new capsule includes an alternative opacifying technology
that provides a good masking solution as well as enhanced light protection for
the fill formulation. In December 2021, Repligen bought Newton, New
Jersey-based BioFlex Solutions. The purchase adds to and enhances Repligen’s
single-use fluid management product line, as well as simplifies its supply
chain. The integration of BioFlex Solutions strengthens its system offering by
further integrating components and assemblies.
Related the Press Release@ Downstream Processing Market Report
Downstream Processing Market
Report Highlights
- Chromatography systems accounted for the largest revenue share in
2021 owing to the high adoption of chromatography for biopharmaceutical
purification
- The advent of single-use chromatography systems that bring an 80.0%
reduction of the use of water and chemicals for buffer has further
increased the adoption of chromatography for downstream processing of
bio-therapeutics
- Filters are anticipated to grow at a lucrative rate over the
forecast period. Efforts undertaken by the key players to develop
intelligent membranes for purification & separation is fuelling the
market growth
- Purification by chromatography accounted for the largest revenue
share as it can be employed across all steps of a downstream process. The
technique is also crucial in bioprocessing to obtain pure biologics
- Antibiotic production dominated the market in 2021 owing to
the wide use of antibiotics for the treatment of a variety of
clinical disorders including infectious diseases and cancer
- A rise in occurrences of antibiotic resistance also propels the
industrial-scale development of novel antibiotic candidates
- North America dominated the global market in 2021 owing to the
presence of large in-house biopharmaceutical manufacturing facilities
- Asia Pacific will register the fastest CAGR from 2022 to 2030 due
to a rise in contract development services in emerging economies
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