The global Downstream Processing Market size is expected to reach USD 94.79 billion by 2030, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 14.84% from 2023 to 2030. The capacity requirements during the development of biologic drugs have changed over the past few years, wherein the demand for manufacturing high-volume products has shifted to developing small-volume, high-potency products. This creates new avenues for single-use technologies. A rise in the utilization of downstream processing techniques for the development of COVID-19 vaccines is a significant factor driving the market. The adoption of small-scale, single-use systems for process development and downstream processing is already high.
Thus,
evolutionary changes are expected in the area of single-use technologies for
manufacturing small-volume, highly-potent drugs. The development of novel film
chemistries, closed systems, automation in clinical-scale single-use systems,
and smart sensors are some noteworthy advancements in the field. A rise in
applications of downstream processing for the production of biopharmaceuticals
is expected to bring growth opportunities to the market. This has also led to
an increase in strategic deals and development in the market. For instance, in
February 2021, Evozyne, LLC collaborated with a leading rare disorders drug
manufacturer for the production and marketing of novel biopharmaceuticals for
immune modulation.
Key
players are investing in the bioprocessing of vaccines and therapies for
COVID-19 to increase their market share. For instance, in May 2022, Lonza and
ALSA Ventures are partnering to provide biotech firms with development and
manufacturing services. In May 2022, Lonza added Titanium Dioxide-free
white hard gelatin capsules to its Capsugel Capsule Line. The new capsule
includes an alternative opacifying technology that provides a good masking
solution as well as enhanced light protection for the fill formulation. In
December 2021, Repligen bought Newton, New Jersey-based BioFlex Solutions. The
purchase adds to and enhances Repligen’s single-use fluid management product
line, as well as simplifies its supply chain. The integration of BioFlex
Solutions strengthens its system offering by further integrating components and
assemblies.
Related Press
Release@ Downstream Processing Market Report
List of Key Players of Downstream Processing Market
- Merck KGaA
- Sartorius
Stedim Biotech S.A
- GE
Healthcare
- Thermo
Fisher Scientific Inc.
- Danaher
Corporation
- Repligen
- 3M Company
- Boehringer
Ingelheim International GmbH
- Corning
Corporation
- Lonza Group
Ltd
- Dover
Corporation
- Ashai Kasei
- Ferner PLC
- Eppendorf AG
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Downstream Processing Market Report Highlights
- The
chromatography systems segment dominated the market for downstream
processing and accounted for the largest revenue share of 41.29% in 2022
- The advent
of single-use chromatography systems that bring an 80.0% reduction of the
use of water and chemicals for buffer has further increased the adoption
of chromatography for downstream processing of bio-therapeutics
- Filters are
anticipated to grow at a lucrative rate over the forecast period. Efforts
undertaken by the key players to develop intelligent membranes for
purification & separation is fuelling the market growth
- Purification
by chromatography accounted for the largest revenue share as it can be
employed across all steps of a downstream process. The technique is also
crucial in bioprocessing to obtain pure biologics
- The
antibiotic production segment dominated the market for downstream
processing and generated the largest revenue share of 32.48% in 2022 owing
to the wide applications of antibiotics for the treatment of several
disorders.
- A rise in
occurrences of antibiotic resistance also propels the industrial-scale
development of novel antibiotic candidates
- North
America dominated the market for downstream processing with the largest
revenue share of 34.57% in 2022 owing to government support for promoting
bioprocess technologies, rising medical expenditure, and developed
healthcare infrastructure.
- Asia Pacific
expected to register the highest growth rate of 15.67% during 2023-2030
due to a rise in contract development services in emerging economies
Downstream Processing Market Segmentation
Grand
View Research has segmented the global downstream processing market based on
product, technique, application, and region:
Downstream Processing Product Outlook (Revenue, USD
Billion, 2018 - 2030)
- Chromatography
Systems
- Filters
- Evaporators
- Centrifuges
- Dryers
- Others
Downstream Processing Technique Outlook (Revenue, USD
Billion, 2018 - 2030)
- Cell
Disruption
- Solid-liquid
separation
- Filtration
- Centrifugation
- Concentration
- Evaporation
- Membrane
filtration
- Purification
by Chromatography
- Formulation
Downstream Processing Application Outlook (Revenue, USD
Billion, 2018 - 2030)
- Antibiotic
Production
- Hormone
Production
- Antibodies
Production
- Enzyme
Production
- Vaccine
Production
Downstream Processing Regional Outlook (Revenue, USD
Billion, 2018 - 2030)
- North
America
- U.S.
- Canada
- Europe
- Germany
- U.K.
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- Japan
- China
- India
- South Korea
- Thailand
- Australia
- Latin
America
- Brazil
- Mexico
- Argentina
- Middle East
and Africa (MEA)
- South
Africa
- Saudi
Arabia
- UAE
- Kuwait
Grand View Research, Inc. is a U.S. based market research and consulting company, registered in the State of California and headquartered in San Francisco. The company provides syndicated research reports, customized research reports, and consulting services. To help clients make informed business decisions, the company offers market intelligence studies ensuring relevant and fact-based research across a range of industries including technology, chemicals, materials, healthcare and energy.
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Corporate Sales Specialist, USA
Grand View Research, Inc
Phone: 1-415- 349-0058
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Email: sales@grandviewresearch.com
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