The global Protein Expression Market size is expected to reach USD 6.51 billion by 2030, according to a new report by Grand View Research, Inc., expanding at a CAGR of 10.22% from 2024 to 2030. The increasing research in proteomics and genomics, the rising incidence of chronic diseases, and escalating demand for biologic products around the globe are enhancing the demand for protein expression, which is likely to drive the market. For instance, in April 2022, in a research published on Frontiers Media S.A., researchers differentially expressed 22 proteins to identify potential diagnostic biomarkers for Multiple Sclerosis (MS).
An increase in
R&D investments by the players is estimated to have a considerable impact
on the usage of protein expression. In August 2022, the managing director of
Biocon Biologics stated in one of his interviews that the overall cost of the
R&D is 12-14% of revenues. The investment is essential to build a
sustainable portfolio of around 20 biosimilar molecules and the company is anticipated to launch
at least once every 1-2 years. The approximate cost of developing these
molecules is USD 50-100 million.
Other determinants
such as rapid acceleration in the demand for protein therapeutics and government
investment in the applications of the protein expression industry are also
supporting the market growth. For instance, in May 2022, Proteomics
International Laboratories was awarded approximately USD 286,833 funding from
the Australian Government under the Medical Research Future Fund (MRFF)
initiative. The funding is expected to support the manufacturing of the
PromarkerD test in Australia. Such financial assistances are likely to
supplement the market growth in the coming years.
The outbreak of
the COVID-19 pandemic developed the urge to profile and conduct differential
gene expression analyses on COVID-19 patients. Research published in Briefings
in Bioinformatics, March 2021, employed the data of protein-drug interaction to
identify the prospective drugs for COVID-19. As a result, the usage of the
process is projected to upsurge during the COVID-19 pandemic and contribute to
market growth.
The growing
requirement for personalized therapy and vaccine is expected to be the key
factor fueling the market growth during the forecast period. For instance, in
January 2022, Amgen announced a collaboration with Generate Biomedicines to
discover and develop protein therapeutics for various areas. The companies are
estimating the worth of this collaboration around USD 1.9 billion.
The increasing
development of recombinant proteins for industrial use, such as the production
of food and beverages, is anticipated to boost the use of protein expression in
the non-healthcare sector. However, the retail pricings of recombinant proteins
for industrial and pharmaceutical uses are drastically different as
pharmaceutical proteins are sold for billions of dollars per kg, while
industrial proteins for tens of dollars per kg. R&D, clinical trials, and
patents are the additional requirements of pharmaceutical proteins.
List of Key
Players of Protein Expression Market
- Agilent Technologies, Inc.
- Bio-Rad Laboratories
- Thermo Fisher Scientific, Inc.
- Merck Millipore
- New England BioLabs, Inc.
- Promega Corporation
- QIAGEN
- Takara Bio, Inc.
- Oxford Expression Technologies
- Lucigen Corporation
Related Press Release@ Protein Expression Market Report
Protein Expression
Market Report Highlights
- The prokaryotic segment held the largest market
share of 41.37% in 2023. Since it is relatively easier to handle and
fulfill major purposes in research.
- In 2023, reagents dominated the market with a
leading market share of 44.44%. The market consists of mature players such
as Agilent Technologies, Inc.
- The therapeutic segment held the highest market
share with 52.05% in 2023. Since protein therapeutic poses numerous
advantages over other medications.
- The pharmaceutical and biotechnological companies
segment held the maximum market share in 2023 with 46.50%.
- North America protein expression market dominated
the global market with a 36.11% share in 2023.
Protein Expression Market Report
Scope
Report Attribute |
Details |
Market
size value in 2024 |
USD 3.63
billion |
Revenue
forecast in 2030 |
USD 6.51
billion |
Growth
rate |
CAGR of
10.22% from 2024 to 2030 |
Actual
data |
2018 -
2023 |
Forecast period |
2024 - 2030 |
Protein Expression
Market Segmentation
Grand View
Research has segmented the global protein expression market on the basis of
expression systems, product, application, end use, and region:
Protein
Expression Systems Outlook (Revenue, USD Million, 2018 - 2030)
- Prokaryotic
- Mammalian cell
- Insect cell
- Yeast
- Others
Protein
Expression Product Outlook (Revenue, USD Million, 2018 - 2030)
- Reagents
- Competent cells
- Expression vectors
- Services
- Instruments
Protein
Expression Application Outlook (Revenue, USD Million, 2018 - 2030)
- Therapeutic
- Industrial
- Research
Protein
Expression End Use Outlook (Revenue, USD Million, 2018 - 2030)
- Pharmaceutical and biotechnological companies
- Academic research
- Contract research organizations
- Others
Protein
Expression Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- UK
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- China
- Japan
- India
- South Korea
- Australia
- Thailand
- Latin America
- Brazil
- Argentina
- MEA
- South Africa
- Saudi Arabia
- UAE
- Kuwait
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