The global plasmid purification market size is anticipated to reach USD 3.69 billion by 2030 and is projected to grow at a CAGR of 11.60% from 2024 to 2030, according to a new report by Grand View Research, Inc. Rising acceptance of cell & gene therapy and growing demand for recombinant technology products are factors contributing to market growth. Moreover, technological advancements in plasmid purification further propel market growth.
Plasmids
are crucial in gene therapy and genetic medicine. Their unique properties allow
them to serve as effective vectors for delivering therapeutic genes into target
cells. Plasmids function by introducing exogenous genes into specific
cells to correct or replace defective genes responsible for diseases. Moreover,
with the increasing acceptance and application of gene therapy for treating
various diseases, there is a growing need for purified plasmid DNA. In gene
therapy, plasmids serve as vectors for delivering therapeutic genes.
Researchers
design plasmids to carry therapeutic genes, including normal copies of mutated
genes, genes encoding proteins to combat disease, or RNA molecules like shRNA
that can silence harmful genes. Plasmid purification is critical in the
development and application of gene therapy. Contaminants such as chromosomal
DNA, proteins, endotoxins, and residual bacterial components can interfere with
the efficacy and safety of the therapeutic product. Thus, advancements in
purification technologies enhance the yield and quality of plasmid DNA,
facilitating the scalability of plasmid production, which is essential for
meeting the increasing demands of gene therapy development.
The
COVID-19 pandemic has significantly impacted the market growth. The increased
demand for synthetic biology products, driven by the urgent need for COVID-19
vaccines and treatments, has accelerated research and development (R&D) in
cloning technology. This surge in R&D activities in synthetic biology has
led to increased funding and investment in companies involved in vaccine
development, diagnostics, and therapeutic research. Moreover, despite the
challenges posed by the pandemic, the market is expected to continue growing
steadily due to the increasing adoption of novel technologies, the rising
demand for gene therapies, and ongoing advancements in genetic engineering.
However,
one of the primary concerns of the market is the ethical constraints related to
the use of recombinant DNA technology is the misuse of gene cloning and
synthesis technology in the creation of harmful pathogens through synthetic
biology techniques to develop bioweapons. Improper handling or disposal of
synthetic DNA and plasmids could lead to environmental contamination.
Engineered organisms released into the environment could have ecological
consequences.
List
of Key Players in the Plasmid Purification Market
- Merck KGaA
- QIAGEN
- Thermo Fisher
Scientific, Inc.
- Takara Bio
- Promega
Corporation
- Zymo Research
- MP
BIOMEDICALS
- New England
Biolabs
- MCLAB
- Applied
Biological Materials Inc.
Request a free sample copy or view report
summary: Plasmid Purification Market Report
Plasmid
Purification Market Report Highlights
- The products
segment led the market with the largest revenue share of 72.93% in 2023,
as the use of specialized kits and reagents significantly enhances the
efficiency, reliability, and quality of the purification process.
Furthermore, the services segment is anticipated to experience at a
significant CAGR of 12.58% from 2024 to 2030
- Based on
grade, the molecular grade segment led the market with the largest revenue
share of 58.42% in 2023, as these plasmids are engineered to be easily
manipulated and modified, allowing researchers to make precise changes to
the genetic material. The transfection grade segment is anticipated to
grow at the fastest CAGR of 13.24% over the forecast period
- Based on
application, the cloning & protein segment led the market with the
largest revenue share of 48.76% in 2023, owing to the growing demand for
genetically modified crops and organisms. Furthermore, the transfection
& gene editing segment is expected to grow at the fastest CAGR over
the forecast period.
- Based on end
use, the academic & research institutes segment led the market with
the largest revenue share of 40.12% in 2023, driven by their significant
contribution to R&D to bring novel gene therapy treatments and
engineered biotechnological products to market. Also, the contract
research organizations segment is expected to expand at the fastest CAGR
of 13.38% during the forecast period, due to their increasing adoption and
investment in advanced research and manufacturing technologies
- North America
dominated the market with the largest revenue share of 40.58% in 2023,
owing to factors such as increasing investments in R&D activities,
rising demand for personalized
medicine, and advanced biotechnology research infrastructure
Plasmid
Purification Market Segmentation
Grand
View Research has segmented the global plasmid purification market based on
product & service, grade, application, end-use, and region:
Plasmid
Purification Product & Service Outlook (Revenue, USD Million, 2018 - 2030)
- Products
- Instruments
- Kits &
Reagents
- Services
Plasmid
Purification Grade Outlook (Revenue, USD Million, 2018 - 2030)
- Molecular
Grade
- Transfection
Grade
Plasmid
Purification Application Outlook (Revenue, USD Million, 2018 - 2030)
- Cloning &
Protein Expression
- Transfection
& Gene Editing
- Others
Plasmid
Purification End Use Outlook (Revenue, USD Million, 2018 - 2030)
- Pharmaceutical
& Biotechnology Companies
- Academic
& Research Institutes
- Contract
Research Organizations
Plasmid
Purification Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- UK
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- China
- Japan
- India
- South Korea
- Australia
- Thailand
- Latin America
- Brazil
- Argentina
- MEA
- South Africa
- Saudi Arabia
- UAE
- Kuwait
About Us:
Grand
View Research, Inc. is a U.S. based market research and consulting company,
registered in the State of California and headquartered in San Francisco. The
company provides syndicated research reports, customized research reports, and
consulting services. To help clients make informed business decisions, the
company offers market intelligence studies ensuring relevant and fact-based
research across a range of industries including technology, chemicals,
materials, healthcare and energy.
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